How Accurate Are Mouth Swab Drug Tests? (2024)

A mouth swab drug test screens for substances in your system, such as illicit drugs, prescription medications, alcohol, or marijuana. The test is performed using an oral swab that collects saliva.

Results of swab drug tests, also known as saliva drug tests or oral fluids drug tests, are often available within minutes. While used less often than urine testing, saliva screenings are common, and the results are considered highly accurate.

A variety of drugs and substances can be detected by a mouth swab test. However, it's important to understand the limitations of these tests and your legal rights when you're being tested.

How Accurate Are Mouth Swab Drug Tests? (1)

How Does a Mouth Swab Drug Test Work?

An oral fluid test is quick and easy. You may have the screening done at a lab or testing site, but this kind of test can also be done on the roadside by a police officer.

To ensure accurate results, follow these steps.

  • Don't eat or drink for 10 minutes prior to the test.
  • Before an oral swab, the tester will check your mouth to ensure there's no substance or device present that could interfere with collecting a clean sample.
  • A sterilized swab is placed inside the mouth to collect saliva secreted from glands.
  • The swab is removed and placed into a collection container.
  • Depending on the type of test, the results may be analyzed immediately and results available in minutes, or the sample may need to be sent to a lab overnight for testing.

If you suffer from dry mouth or have difficulty generating enough saliva, the tester can give you water, which you can drink or use to rinse your mouth. You will then need to wait 10 minutes before the sample can be collected.

Why You Can't Eat or Drink

Certain foods or drinks can change the pH (acid-base) level of saliva and can alter the test results, potentially causing a false positive or false negative result. This includes vinegar, citrus, bicarbonate, fruit juices, and salt. Even chewing gum needs to be avoided to ensure that the results are not tainted.

Home testing kids are also available. You need to follow the instructions for these carefully. In some instances, you may need to complete the self-test under supervision.

When Are Mouth Swab Drug Tests Used?

Saliva drug tests are quick and easy ways to check for drug use or monitor health. They are commonly used for the following situations:

  • Pre-employment qualification
  • Periodic workplace evaluation
  • Pain management monitoring
  • Substance abuse treatment
  • Impaired driver testing

Employers and healthcare facilities often use saliva tests because there are several benefits over other types of drug screenings, including urine tests, blood draws, and hair analyses. These advantages include:

  • Relatively inexpensive
  • Quick and convenient
  • Can detect current usage
  • Receive results in minutes
  • Rapid tests are difficult to cheat because the tester is there with you the entire time

What Do Oral Fluid Screenings Test For?

Mouth swab drug tests can detect a variety of different substances. The following are among the things that might show up in a mouth swab screen:

  • Alcohol
  • Amphetamines (including crystal meth)
  • Barbiturates
  • Benzodiazepines
  • Cocaine
  • Gamma-hydroxybutyrate (GHB)
  • Ketamine ("special K")
  • Marijuana (THC)
  • MDMA ("ecstasy")
  • Methamphetamine
  • Methadone
  • Opiates (like morphine and heroin)
  • Opioids (like hydrocodone, oxycodone, and fentanyl)
  • Performance-enhancing drugs (like anabolic steroids)
  • Phencyclidine (PCP)
  • Rohypnol ("roofies")

How Accurate Is a Mouth Swab Drug Test?

If the mouth swab drug test is performed correctly, the test can be highly accurate, sporting a sensitivity of up to 100% and a specificity of 86% for certain drugs. (Sensitivity refers to the percentage of correct positive results, while specificity refers to the percentage of correct negative results.)

It is still possible for some tests to give inaccurate readings. For instance, false positive rates for oral fluid screenings for cannabis, cocaine, methamphetamine, and opioids are between 3% and 7%.

Also, some drugs are not well detected by the current generation of tests. The drugs for which saliva-based tests are least accurate are benzodiazepines and amphetamines,

Factors Influencing Results

In addition to eating and drinking before the test, there are other factors that can influence the accuracy of saliva testing, such as:

  • Your age (which can impact how quickly or slowly a drug is metabolized)
  • Your liver or kidney function (which can increase or decrease how fast a drug leaves the system)
  • How much of a substance you consumed (large doses vs. smaller doses)
  • How frequently a substance is used (as certain drugs can accumulate in the system)
  • The quality of the substance (as some drugs are "cut" with inactive fillers)

How Long After Use Can a Drug Be Detected?

In many cases, a drug can be detected in saliva as early as one hour after a dose. Thereafter, substances can remain detectable from several hours to several days before gradually dropping to undetectable levels. In general, drugs stay in saliva anywhere from five to 48 hours.

The following are the average windows for when drugs are detectable in oral fluid.

DrugDetectable in saliva (estimated)
Alcohol12 to 24 hours
Cannabis/marijuana24 to 48 hours
Cocaine3 days
Codeine24 to 48 hours
Ecstasy2 days
Fentanyl24 to 48 hours
Heroin5 hours
Hydrocodone24 to 48 hours
Methadone2 days
Morphine4 days
Nicotine5 days
Oxycodone3 days

Urine tests are usually able to detect substances that were used further back, but there are more challenges to testing including the risk of urine samples being manipulated. This can include people adding substances to the urine sample or submitting other people's urine for testing.

Legal Considerations

If you work in an industry related to transportation, national safety, or public safety, you may be required by law to undergo regular drug testing. These include jobs regulated by the Department of Transportation.

Depending on the regulations, people who test positive may be directed to a substance abuse program (which means you may not be immediately dismissed for having tested positive).

Laws for other industries vary by state. Testing oral fluids via a mouth swab is not allowed in Hawaii, Maine, Puerto Rico, and Vermont.

Most other states allow the use of oral swabs for employee drug testing, albeit with limitations and restrictions. To find out about the laws in your state, contact the American Civil Liberty Union (ACLU) at 212-549-2500.

Where to Find Help

If you or a loved one is struggling with an alcohol or substance use disorder, call the Substance Abuse and Mental Health Services Administration (SAMHSA) National Helplineat1-800-662-4357for information on support and treatment facilities in your area. Know that you are not alone.

Summary

Mouth swab drug tests are a drug screening tool that uses saliva to detect various substances in your system. These tests are painless and quick, sometimes delivering results in minutes. Mouth swab tests are usually best for detecting recent drug use. Mouth swab drug tests are typically used to detect alcohol, amphetamines, cocaine, marijuana, opioids, and more.

13 Sources

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

  1. National Institute on Drug Abuse. Drug Testing.

  2. Desrosiers NA, Huestis MA. Oral fluid drug testing: analytical approaches, issues and interpretation of results. J Anal Toxicol.2019 Jul 24;43(6):415-443. doi:10.1093/jat/bkz04

  3. Substance Abuse and Mental Health Services. Oral Fluid Specimen Collection Handbook for Federal Agency Workplace Drug Testing Programs.

  4. Anizan S, Huestis MA. The potential role of oral fluid in antidoping testing. Clin Chem. 2014 Feb;60(2):307–322. doi:10.1373/clinchem.2013.209676

  5. MedlinePlus. Drug Testing.

  6. Musshoff F, Hokamp EG, Bott U, Madea B. Performance evaluation of on-site oral fluid drug screening devices in normal police procedure in Germany. Forensic Sci Int.2014 May:238:120-4 doi:10.1016/j.forsciint.2014.02.005

  7. Beirness, D. J., & Smith, D. R. (2016). An assessment of oral fluid drug screening devices.Canadian Society of Forensic Science Journal,50(2), 55–63. doi:10.1080/00085030.2017.1258212

  8. Canadian Centre on Substance Abuse and Addiction. Oral fluid drug screening.

  9. Dziurkowska E, Wesolowski M. Effects of age, drug dose, and sampling time on salivary levels of olanzapine, quetiapine, and their metabolites. J Clin Med. 2020 Oct;9(10):3288. doi:10.3390/jcm9103288

  10. Indiana State Government. Drug Detection Times.

  11. Fu S. Adulterants in Urine Drug Testing.Adv Clin Chem. 2016;76:123-163. doi:10.1016/bs.acc.2016.05.003

  12. Substance Abuse and Mental Health Services Administration.Considerations for safety- and security-sensitive industries.

  13. American Civil Liberties Union. State-by-state workplace drug testing laws.

How Accurate Are Mouth Swab Drug Tests? (2)

By Molly Burford
Molly Burford is a mental health advocate and wellness book author with almost 10 years of experience in digital media.

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How Accurate Are Mouth Swab Drug Tests? (2024)

FAQs

How Accurate Are Mouth Swab Drug Tests? ›

A mouth swab drug test is relatively accurate—but only when used correctly.

What shows up in a mouth swab drug screen? ›

Mouth swab tests are usually best for detecting recent drug use. Mouth swab drug tests are typically used to detect alcohol, amphetamines, cocaine, marijuana, opioids, and more.

What can make you fail a saliva drug test? ›

Can substances such as food, beverages, over-the-counter medication, and mouthwash affect the oral fluid drug test results? Yes. For this reason, the donor is to refrain from consumption of food or beverages for 10 minutes prior to specimen collection.

Does chewing gum affect saliva drug tests? ›

Oral fluid production is stimulated by use of agents such as citric acid candy, chewing gum or other agents. This will inevitably change the pH and concentration of drug in the oral fluid.

Why do employers use mouth swab drug tests? ›

Lab-based oral fluid testing offers some notable advantages for employers to consider. Its ability to detect recent use sooner following ingestion than is the case with urine or hair makes it a preferred sampling method for reasonable suspicion and post-accident testing scenarios.

What should you not do before a saliva drug test? ›

Food, beverages, medication, and mouthwash can all interfere with accurate saliva drug test results. The specimen will either be instantly analyzed on-site or sent to a lab to determine if traces of controlled substances are present in the individual's body.

What is the most common false positive drug test? ›

Amphetamine (more on this below) and methamphetamine are the most commonly reported false positive.

What foods to avoid before urine drug test? ›

Patient must have diet free of avocados, bananas, tomatoes, plums, eggplant, hickory nuts, walnuts, pineapple and mollusks for 2 days prior to and during the collection. If advised by a physician, the patient should be off all drugs for 3 days. Restrict caffeine, nicotine and alcohol for 24 hours prior to collection.

Can I sue for a false positive drug test? ›

Current case law indicates that in the context of drug testing, an employer or independent testing firm may be liable for negligence when tests are improperly administered, when test results are inaccurately maintained, and when an employee who has tested positive for drugs injures a third person.

What can cause a false negative drug test? ›

False-negative results occur when a drug or metabolite is present at such low levels that it is not detected. Confirmatory testing is essential to distinguish a true negative from a false negative. Contaminants can also interfere with the immunoassay's ability to detect the presence of drugs.

How to dispute a false positive drug test? ›

If this happened in your case, ask for a retest of your sample. If your employer for some reason doesn't believe your explanation of the positive result, and your retest comes up positive again, it's time to talk to an experienced employment lawyer about the best way to protect your rights.

Can mouthwash cause a positive drug test? ›

Mouthwash and Breath Strips: Most mouthwashes (Listermint®, Cepacol®, etc.) and other breath cleansing products contain ethyl alcohol. The use of mouthwashes containing ethyl alcohol can produce a positive test result.

How long can alcohol be detected with a mouth swab? ›

Alcohol detection tests can measure alcohol in the blood for up to 12 hours, on the breath for 12 to 24 hours, urine for 12-24 hours (72 or more hours after heavier use), saliva for up to 12 hours, and hair for up to 90 days.

What is the difference between a mouth swab and a urine drug test? ›

When compared to urine and hair drug tests, oral fluid is best at detecting recent drug use. Drugs take time to metabolize and pass through the system in a urine test, and the same drugs are incorporated as hair grows and it takes time for the drug to be present in the hair above the scalp.

Is DOT approving saliva based drug testing? ›

HHS Approval and Implementation Timeline: The HHS approved oral fluid testing, with DOT's final rule effective from June 1, 2023, however employers cannot use oral fluid testing for DOT regulated tests until laboratories and collection devices are certified.

What type of drug test does LabCorp use for employment? ›

What testing methodology does Labcorp use to perform initial drug screening? Labcorp performs initial drug screening using immunoassay. An immunoassay is a test that uses antibodies to detect the presence of drugs and other substances in urine.

What diseases can be detected by a mouth swab? ›

Saliva has been reliably used to detect HIV-1 and -2, and viral hepatitis A, B and C. It can also be used to monitor a variety of drugs including marijuana, cocaine and alcohol (1). There are compelling reasons to use saliva as a diagnostic fluid to monitor health and diseases.

How long does a saliva drug test take to get back? ›

Results for specimens that screen negative for all drugs are generally available within 24-36 hours after specimens are received at the laboratory. Results for confirmation testing of presumptive positive screens are usually available within an additional 72 hours.

How long can alcohol be detected in a mouth swab? ›

Alcohol detection tests can measure alcohol in the blood for up to 12 hours, on the breath for 12 to 24 hours, urine for 12-24 hours (72 or more hours after heavier use), saliva for up to 12 hours, and hair for up to 90 days. The half-life of alcohol is between 4-5 hours.

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